Portrait of Nikolaj T. Mücke

Nikolaj Takata Mücke

Postdoc · Delft University of Technology

I am a postdoc at Delft University of Technology, the Netherlands, working at the intersection of scientific computing and deep learning. My research focuses on generative models, uncertainty quantification, data assimilation, physics-consistent machine learning, and fluid dynamics.

More broadly, I am interested in numerical methods and surrogate modelling for partial differential equations and their applications in computational science and engineering — particularly the development of generative and reduced order models for parameterized PDEs, and applying these to efficient, real-time solving of inverse problems and data assimilation with uncertainty quantification in physics applications.

Publications

Integrating Score-Based Diffusion Models with Machine Learning-Enhanced Localization for Advanced Data Assimilation in Geological Carbon Storage

Published in Computational Geosciences

Physics-Aware Generative Models for Turbulent Fluid Flows Through Energy-Consistent Stochastic Interpolants

Published in Computers & Fluids

Generative Super-Resolution of Turbulent Flows via Stochastic Interpolants

Published in Scientific Reports

The Deep Latent Space Particle Filter for Real-Time Data Assimilation with Uncertainty Quantification

Published in Scientific Reports

AI enhanced data assimilation and uncertainty quantification applied to Geological Carbon Storage

Published in International Journal of Greenhouse Gas Control

Advancing Data Assimilation and Uncertainty Quantification for CO2 Sequestration through AI-Hybrid Methods

Published in the Proceedings of ECMOR 2024, the European Conference on the Mathematics of Geological Reservoirs

Machine Learning-Based Digital Twin for Water Distribution Network Anomaly Detection and Localization

Published in Engineering Proceedings, presented at WDSA/CCWI 2024

Markov Chain Generative Adversarial Neural Networks for Solving Bayesian Inverse Problems in Physics Applications

Published in the special issue Scientific Machine Learning: Blending of traditional mechanistic modeling with machine learning methodologies in the journal Computers & Mathematics with Applications

A Probabilistic Digital Twin for Leak Localization in Water Distribution Networks Using Generative Deep Learning

Published in Sensors

Reduced Order Modelling for Dispersive and Nonlinear Water Wave Modelling

Published in Proceedings of the 37th International Workshop on Water Waves and Floating Bodies

Reduced Order Modelling for Wave-Structure Modelling

Published in the Proceedings of the 22nd IACM Computational Fluids Conference

Reduced order modeling for parameterized time-dependent PDEs using spatially and memory aware deep learning

Published in Journal of Computational Science

Reduced Order Modeling for Nonlinear PDE-constrained Optimization using Neural Networks

Published at Conference on Decision and Control (CDC)

Experience

Postdoc

Delft University of Technology

I am working as a postdoc in the UrbanAIR project. The goal of the project is to develop a framework for urban air quality and heat dynamics forecasting. My role is specifically focused on the development of data assimilation and uncertainty quantification methods using deep learning techniques.

Postdoc

Centrum Wiskunde & Informatica

Together with Benjamin Sanderse, I developed generative models for physics applications. The aim was to perform probabilistic forecasting and posterior sampling that adhere to the underlying laws of physics.

AI Lead

Spatialise

I was the lead developer of the Spatialise AI platform, SOCMO. My role included the development of MLOps pipelines. This covered data science aspects such as model training, testing, and hyperparameter tuning. Furthermore, I was responsible for the ML engineering aspects such as model deployment, monitoring, and scaling.

PhD Candidate

Centrum Wiskunde & Informatica

My PhD project dealt with deep learning for data assimilation and inverse problems in physics applications. The aim was to perform real-time data assimilation with uncertainty quantification using deep learning techniques. My supervisors were Cornelis Oosterlee and Sander Bohté.

Research Assistant

Technical University of Denmark, DTU Compute

The research project dealt with low noise supercontinuum sources for ultra-high resolution 800nm optical coherence tomography for glaucoma diagnosis. I was working on GPU acceleration of a C++ implementation of the 4th order Runge-Kutta Interaction Picture method to solve the generalized nonlinear Schrödinger Equation as well as uncertainty quantification of the input sources.

Student Assistant

Ørsted, Numerical Competence Centre

My work included programming and mathematical modelling of various elements within the wind energy sector. Examples are time series models for weather with the goal of predicting production time of a wind turbine farm and analyzing buckling capacity of soil supported structures using partial differential equations and optimization techniques.

Science Communicator

Experimentarium

Experimentarium is a science museum, mostly for children and young adults. My job consisted of developing and performing science shows and experiments in front of large crowds and make complicated phenomena understandable and comprehensible for the layman and school classes.

Teaching & Supervision

Supervision

Turbulence Closure Modeling using Stochastic Interpolants

Master thesis, Technical University of Eindhoven

Diffusion Models for Time Series Denoising

Bachelor thesis, Utrecht University

Guidance in Using Robotic-Arm Assisted Surgical System for Knee Arthroplasty

Master thesis, Utrecht University

Stock Price Simulation under Jump-Diffusion Dynamics: A WGANs-Based Framework with Anomaly Detection Techniques

Master thesis, Utrecht University

Hamiltonian Neural Networks for Fluid Flows

Internship, Centrum Wiskunde & Informatica

Traditional and ML approaches to generate and understand implied volatility surfaces

Master thesis, Technical University of Delft
Teaching

Computational Imaging masterclass

Centrum Wiskunde & Informatica — Lecturing

Neural Networks in Finance

Utrecht University — Lecturing, developing material, grading

Scientific Computing for Differential Equations 2 (02687)

Technical University of Denmark — Teaching assistant, grading

Advanced Engineering Mathematics 2 (01025)

Technical University of Denmark — Teaching assistant, grading

Scientific Computing for Differential Equations (02685)

Technical University of Denmark — Teaching assistant, grading

Conferences, Workshops & Masterclasses

Organized by Me

Physics-consistent generative modeling

Minisymposium, ENUMATH 2025

Co-Organizer: Benjamin Sanderse

Deep Learning-Based Latent-Space Models for Scientific Computing

Minisymposium, SIAM Conference on Computational Science and Engineering

Co-Organizer: Wouter Edeling

Workshop Digital Twins for Pipe Transport Networks

Workshop, Centrum Wiskunde & Informatica

Co-Organizers: Prerna Pandey, Shashi Jain, Kees W. Oosterlee, Sander M. Bohte

Machine Learning and Stochastic Modelling for Dynamical Systems

Minisymposium, SIAM Conference on Uncertainty Quantification

Co-Organizer: Wouter Edeling

Workshop on Machine Learning for Physics-Based Modeling

Workshop, Centrum Wiskunde & Informatica

Co-Organizers: Prerna Pandey, Shashi Jain, Kees W. Oosterlee, Sander M. Bohte

AI and IoT for Flow Modeling

Workshop, Centrum Wiskunde & Informatica

Co-Organizers: Shashi Jain, Kees W. Oosterlee, Sander M. Bohte

Education

Degrees

Mathematical Modeling and Computation

Master of Science, Technical University of Denmark

Mathematics and Technology

Bachelor of Science, Technical University of Denmark
Exchange Semesters

Technical University of Munich, Germany

Masters, Fakultät für Mathematik

Adelaide University, Australia

Bachelors
Summer/Winter Schools

International Graduate Summer School on “Frontiers of Applied and Computational Mathematics”

Shanghai Jiao Tong University, China

Experiencing China

Tsinghua University, China

Grants, Awards, & Certifications

Grants

NWO AINed XS Europe Grant

€50,000 for postdoc research project

Oracle Research Grant

€34,000 to be spent on Oracle Cloud Compute resources
Awards

Teaching Assistant of the Year

Awarded by the students at Technical University of Denmark
Certifications

Coursera – Deep Learning Specialization